No. 16 Louisville hosts Wake Forest in an ACC Week 4 game Saturday, Sept. 26, at noon ET. ESPN is the TV channel, and Fubo offers a live stream; regional restrictions may apply.
Louisville is 2-1 after losing its opener to No. 4 Ole Miss, then beating Villanova and then-No. 16 SMU. The Cardinals lead the all-time series 7-3; they last met in 2022, when Louisville won 48-21.
