Wake Forest (2-1) visits No. 16 Louisville (2-1) at noon Saturday, Sept. 26, at L&N Federal Credit Union Stadium; ESPN will televise the game. A win would put the Demon Deacons halfway to bowl eligibility after four weeks; a loss would drop them to .500.
Louisville beat SMU 41-31 in its previous game. Wake Forest’s all-time record against Louisville is 3-7; the Cardinals won the teams’ last meeting, 48-21 in 2022. ESPN’s matchup predictor gives Wake a 20% chance to win, and the listed spread is Wake +12.5.
