No. 16 Louisville (2-1, 1-0 ACC) hosts Wake Forest (2-1, 0-1) at noon Saturday at L&N Stadium, with the game on ESPN. Louisville is favored by 12.5 points; Wake quarterback Gio Lopez averages 295.7 passing yards per game this season.
Louisville leads the all-time series 7-3 and won the last meeting, 48-21 in Louisville on Oct. 29, 2022. The preview highlights a contrast in big plays: Louisville has six touchdowns of at least 50 yards this season, while Wake has allowed three explosive plays and no pass completion of 20 yards or more.
Wake may be without starting running back Ty Clark, who left last weekend’s game with what appeared to be a concussion. True freshman Deuce Lawrence is next in line; the preview says Wake has struggled to run the ball this season.
