FanDuel Sportsbook lists Indianapolis as a 3.5-point favorite against Washington in London, with the Colts at -180 on the moneyline and the over/under at 47.5. Both teams are coming off wins; a victory would put either at 2-2 after an 0-2 start.
Indianapolis beat Houston in Berlin to end a nine-game losing streak. After a second Daniel Jones fumble led to a late Texans touchdown, the Colts won with a 53-yard field goal; their defense had largely kept C.J. Stroud from getting comfortable.
Washington beat Seattle with Jayden Daniels out, as Marcus Mariota threw three touchdowns. A Commanders interception returned for a touchdown broke a fourth-quarter tie and helped secure the win.
