San Francisco beat Arizona 36-30 in Week 3 to improve to 3-0 and take sole possession of the NFC West lead. Brock Purdy threw for 297 yards and four touchdowns, while the 49ers gave up points on four of Arizona’s five second-half possessions.
Purdy completed 15 of 27 passes without a turnover. San Francisco’s defense was short-handed, with Nick Bosa sidelined and rotating players in the secondary; Dre Greenlaw and Gracen Halton also left in the second half. Mike Evans exited after grabbing his right side and was taken to the locker room by cart with a rib/oblique injury; his Week 4 availability was not established.
Eddy Pineiro made a 57-yard field goal but missed two second-half extra points. With 1:36 left and a 29-27 lead, Kyle Shanahan called a play-action pass on second-and-10 at Arizona’s 20-yard line; Purdy found George Kittle for his second touchdown, extending the lead to nine. Christian McCaffrey had 75 rushing yards and a touchdown, while Jordan Watkins caught two passes for 60 yards in his 2026 debut.
